

2025–now · Adult Swim · Running
Common Side Effects follows former high school lab partners Marshall and Frances who begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world's diseases.
Sunday at 23:00 (America/New York)
● Next episode
S02E01 · TBA
2027-01-25
Last aired
S01E10 · Raid
2025-03-31
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TBA
2027-01-24 · 30 min
‘Common Side Effects’ Returns for Season 2 in January on Adult Swim
TheWrap · Oct 9, 2026
We Got a First Look at ‘Common Side Effects’ Season 2
Gizmodo · Jul 25, 2026
Acclaimed Adult Swim Hit ‘Common Side Effects’ Sets S2 Premiere
Animation Magazine · Oct 9, 2026
HBO Max's 100% Rated Sci-Fi Thriller Returns in First Look at Season 2
MovieWeb · Jun 25, 2026
Common Side Effects Season 2 Set for January 24th Debut on Adult Swim
Bleeding Cool News · Oct 9, 2026
Adult Swim’s Common Side Effects Is a Surprisingly Great SF Series
reactormag.com · Dec 3, 2025
Break Out the Blue Mushrooms: ‘Common Side Effects’ Will Return in January
Gizmodo · Oct 9, 2026
Adult Swim's Underrated Animated Series Is The Evolution Of Rick & Morty
ScreenRant · Dec 21, 2025
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